Histiocytosis X involving the thyroid and hypothalamus.

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Histiocytosis X involving the thyroid and hypothalamus.

A case of histiocytosis X involving the thyroid and hypothalamus is reported. A 16 year old female presented with amenorrhoea and diabetes insipidus. She subsequently developed a painful goitre with biochemical hypothyroidism, and stridor. The stridor and goitre responded to cyclophosphamide. Previous publications on the use of cytotoxics in histiocytosis X involving the thyroid are reviewed. W...

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langerhans cell histiocytosis involving maxilla and mandible

langerhans cell histiocytosis is a relatively rare unique disease process characterized by an abnormal proliferation of immature dendritic cells usually affecting children and young adults. jaws are involved in less than 10% of children with the disease while mandibular involvement in young children is uncommon and bilateral affection is very rare. the purpose of this report is to describe a un...

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Langerhans Cell Histiocytosis Involving Maxilla and Mandible

Received: 18 April 2008 Accepted: 8 October 2008 Abstract: Langerhans cell histiocytosis is a relatively rare unique disease process characterized by an abnormal proliferation of immature dendritic cells usually affecting children and young adults. Jaws are involved in less than 10% of children with the disease while mandibular involvement in young children is uncommon and bilateral affection i...

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Thyroid hormone and the developing hypothalamus

Thyroid hormone (TH) plays an essential role in normal brain development and function. Both TH excess and insufficiency during development lead to structural brain abnormalities. Proper TH signaling is dependent on active transport of the prohormone thyroxine (T4) across the blood-brain-barrier and into brain cells. In the brain T4 undergoes local deiodination into the more active 3,3',5-triiod...

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Commentary: "histiocytosis X".

Langerhans’ cell histiocytosis may cause irreversible respiratory failure due to progressive destruction of lung parenchyma and widespread cystic change. Transplantation oVers a therapeutic option. A case is described of recurrence of Langerhans’ cell histiocytosis which was associated with deterioration in lung function four years following bilateral lung transplantation. Patients transplanted...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1991

ISSN: 0032-5473

DOI: 10.1136/pgmj.67.789.680